Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

GUCY1B3 - guanylate cyclase 1, soluble, beta 3

Homo sapiens

Synonyms: GC-S-beta-1, GC-SB3, GCS-beta-1, GCS-beta-3, GUC1B3, ...

Saino, M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of GUCY1B3

Inhibition of angiogenesis in human glioma cell lines by antisense RNA from the soluble guanylate cyclase genes, GUCY1A3 and GUCY1B3 [1].

High impact information on GUCY1B3

Furthermore, subcutaneous tumor formation by U-87MG cells in nude mice was dramatically suppressed to less than 0.05% in volume by transfection of either antisense GUCY1A3 or antisense GUCY1B3, which was accompanied by the significant decrease in vascular index to about 10% [1].

Chemical compound and disease context of GUCY1B3

Here, we report that 2 of 9 human glioma cell lines, CCF-STTG1 and U-87MG, overproduced cyclic GMP (cGMP) and showed increased expression of both or either subunits of soluble GC1, GUCY1A3 and GUCY1B3 [1].

References

Inhibition of angiogenesis in human glioma cell lines by antisense RNA from the soluble guanylate cyclase genes, GUCY1A3 and GUCY1B3. Saino, M., Maruyama, T., Sekiya, T., Kayama, T., Murakami, Y. Oncol. Rep. (2004) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP000214	Anopheles gambiae str. PEST
GUCY1B3	Bos taurus
gcy-34	Caenorhabditis elegans
gcy-37	Caenorhabditis elegans
gcy-32	Caenorhabditis elegans
gcy-35	Caenorhabditis elegans
gcy-36	Caenorhabditis elegans
GUCY1B3	Canis lupus familiaris
gucy1b3	Danio rerio
Gycbeta100B	Drosophila melanogaster
GUCY1B3	Gallus gallus
GUCY1B3	Macaca mulatta
Gucy1b3	Mus musculus
GUCY1B3	Pan troglodytes
Gucy1b3	Rattus norvegicus
gucy1b3	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.