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Gene Review

BF3755  -  aconitase protein

Bacteroides fragilis YCH46

 
 
 
 
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Disease relevance of BF3755

  • A mitochondrial-like aconitase in the bacterium Bacteroides fragilis: implications for the evolution of the mitochondrial Krebs cycle [1].
  • Homology searches indicated that the B. fragilis aconitase is most closely related to aconitases of two other Cytophaga-Flavobacterium-Bacteroides (CFB) group bacteria, Cytophaga hutchinsonii and Fibrobacter succinogenes [1].
 

High impact information on BF3755

  • A nonpolar in-frame deletion of the acnA gene that encodes the aconitase prevented growth in glucose minimal medium unless heme or succinate was added to the medium [1].

References

 
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