Disease relevance of Fibrobacter

• Growth of the ruminal bacteria Fibrobacter succinogenes S85, Ruminococcus flavefaciens FD-1, and R. albus 7 followed Monod kinetics with respect to concentrations of individual pure cellodextrins (cellobiose, cellotriose, cellotetraose, cellopentaose, and cellohexaose) [1].
• Detection of stratified microbial populations related to Chlorobium and Fibrobacter species in the Atlantic and Pacific oceans [2].
• Cellobiose transport by the cellulolytic ruminal anaerobe Fibrobacter (Bacteroides) succinogenes was measured using randomly tritiated cellobiose [3].
• Streptococcus bovis JB1, Prevotella ruminicola B(1)4, Selenomonas ruminantium Z108, Fibrobacter succinogenes S85 and Anaerovibrio lipolytica 5S were incubated with either 14C-peptides (mol. wt, 200-1000) or 14C-amino acids to compare their rates of uptake and metabolism [4].

High impact information on Fibrobacter

• Two adjacent, highly homologous endoglucanase genes, celD and celE from Fibrobacter succinogenes S85, which were separated by an AT-rich 223-nucleotide intergenic region were characterized [5].
• When glucose or cellobiose was provided as an energy source for Fibrobacter succinogenes, there was a transient accumulation (as much as 0.4 mM hexose equivalent) of cellobiose or cellotriose, respectively, in the growth medium [6].
• The outer membrane (OM) of Fibrobacter succinogenes was isolated by a combination of salt, sucrose, and water washes from whole cells grown on either glucose or cellulose [7].
• The xynC gene of Fibrobacter succinogenes S85 codes for a 66.4-kDa xylanase which consists of three distinct domains separated by two flexible regions rich in serine residues [8].
• endAFS, a novel family E endoglucanase gene from Fibrobacter succinogenes AR1 [9].

Chemical compound and disease context of Fibrobacter

• Extracellular beta-galactosidase activity of a Fibrobacter succinogenes S85 mutant able to catabolize lactose [10].
• Antigenic nature of the chloride-stimulated cellobiosidase and other cellulases of Fibrobacter succinogenes subsp. succinogenes S85 and related fresh isolates [11].
• Fibrobacter succinogenes subsp. succinogenes S85 initiated growth on microcrystalline cellulose without a lag whether inoculated from a glucose, cellobiose, or cellulose culture [12].
• Structural analysis of the carbohydrate components of the outer membrane of the lipopolysaccharide-lacking cellulolytic ruminal bacterium Fibrobacter succinogenes S85 [13].
• The phylogenetic placement of the rumen bacterium Fibrobacter succinogenes was determined using a signature sequence approach that allows determination of the relative branching order of the major divisions among Bacteria [Gupta, R. S. (2000) FEMS Microbiol Rev 24, 367-402] [14].

Biological context of Fibrobacter

• Phosphorylation of glucose by a guanosine-5'-triphosphate (GTP)-dependent glucokinase in Fibrobacter succinogenes subsp. succinogenes S85 [15].
• Oxidation of the isolated catalytic domain B of xylanase C (XynC-B) from Fibrobacter succinogenes with N-bromosuccinimide (NBS) resulted in the modification of five of the seven Trp residues present in the enzyme [16].

Gene context of Fibrobacter

• Fibrobacter succinogenes lacked xylose isomerase and xylulokinase [17].
• Properties of the recombinant proteins derived from Fibrobacter succinogenes endoglucanase F (EGF), AD2 and AD4, were characterized using surface plasmon resonance [18].
• On the basis of partial 16S rRNA sequences of six Fibrobacter strains, four hybridization probes were designed to discriminate between the species Fibrobacter succinogenes and Fibrobacter intestinalis and to identify F. succinogenes subsp. succinogenes [19].
• The endoglucanase gene (endC) of Fibrobacter succinogenes BL2 encodes a protein of 620 amino acids (EGC) that shows similarity with family E1 cellulases, and particularly with EGB from F. succinogenes S85 [20].

Analytical, diagnostic and therapeutic context of Fibrobacter

• Gene sequence analysis and properties of EGC, a family E (9) endoglucanase from Fibrobacter succinogenes BL2 [20].

References