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Gene Review

Ngf  -  nerve growth factor (beta polypeptide)

Rattus norvegicus

Synonyms: Beta-NGF, Beta-nerve growth factor, Ngfb, beta-NGF
 
 
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Disease relevance of Ngfb

  • In C6-2B astrocytoma cells the Beta NGF content and secretion rate are increased by isoproterenol activation of beta-adrenergic receptors (Schwartz and Costa, 1977) [1].
 

High impact information on Ngfb

  • These results are consistent with the hypothesis that regulation of Beta NGF synthesis in neuroglial cells may be modulated by beta-adrenergic receptor activation [1].
  • Furthermore, addition of dibutyryl-cAMP induces an increase of Beta NGF mRNA content similar to that obtained with isoproterenol [1].
  • Developmental profiles of growth-associated protein (Gap43), Ngfb, Bndf and Ntf4 mRNA levels in the rat forebrain after exposure to 60 Hz magnetic fields [2].

References

  1. Beta-adrenergic receptor regulation of NGF-mRNA content in rat C6-2B glioma cells. Dal Toso, R., De Bernardi, M.A., Costa, E., Mocchetti, I. Neuropharmacology (1987) [Pubmed]
  2. Developmental profiles of growth-associated protein (Gap43), Ngfb, Bndf and Ntf4 mRNA levels in the rat forebrain after exposure to 60 Hz magnetic fields. Harry, G.J., Bartenbach, M., Haines, W., Bruccoleri, A. Radiat. Res. (2000) [Pubmed]
 
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