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Gene Review

IDH2  -  isocitrate dehydrogenase 2 (NADP+),...

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High impact information on IDH2

  • Mitochondrial NADP(+)-specific isocitrate dehydrogenase (IDP) was co-purified with the pyruvate dehydrogenase complex from bovine kidney mitochondria [1].
  • Structural analyses of the deduced proteins of IDP isoenzymes from different species indicated that similarity exists in certain regions, which may represent the common domains for the active sites or coenzyme-binding sites [1].


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