Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

RpL5 - Ribosomal protein L5

Drosophila melanogaster

Synonyms: 60S ribosomal protein L5, CG17489, Dmel\CG17489, E-2d, L5, ...

Marygold, S.J. et al., Coelho, C.M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on RpL5

The three other enhancers encode factors required for mRNA translation: pixie encodes the Drosophila ortholog of yeast RLI1, and RpL5 and RpL38 encode proteins of the large ribosomal subunit [1].

Biological context of RpL5

We have identified point mutations in RpL38 and RpL5 in a screen for factors limiting for growth of the D. melanogaster wing [2].
Surprisingly, we find that RpL38(-)/+ and RpL5(-)/+ adult flies have abnormally large wings as a result of increased cell size, emphasizing the importance of translational regulation in the control of growth [2].
Genetic analysis of RpL38 and RpL5, two minute genes located in the centric heterochromatin of chromosome 2 of Drosophila melanogaster [2].

References

A genetic screen for dominant modifiers of a small-wing phenotype in Drosophila melanogaster identifies proteins involved in splicing and translation. Coelho, C.M., Kolevski, B., Walker, C.D., Lavagi, I., Shaw, T., Ebert, A., Leevers, S.J., Marygold, S.J. Genetics (2005) [Pubmed]
Genetic analysis of RpL38 and RpL5, two minute genes located in the centric heterochromatin of chromosome 2 of Drosophila melanogaster. Marygold, S.J., Coelho, C.M., Leevers, S.J. Genetics (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

RL5_ANOGA	Anopheles gambiae str. PEST
ATL5	Arabidopsis thaliana
RPL5B	Arabidopsis thaliana
AGOS_ACR104C	Ashbya gossypii ATCC 10895
RPL5	Bos taurus
rpl-5	Caenorhabditis elegans
RPL5	Canis lupus familiaris
rpl5a	Danio rerio
rpl5b	Danio rerio
RPL5	Gallus gallus
RPL5	Homo sapiens
KLLA0D06941g	Kluyveromyces lactis NRRL Y-1140
LOC705979	Macaca mulatta
MGG_07048	Magnaporthe oryzae 70-15
Rpl5	Mus musculus
NCU04331	Neurospora crassa OR74A
Os01g0896800	Oryza sativa Japonica Group
RPL5	Pan troglodytes
Rpl5	Rattus norvegicus
RPL5	Saccharomyces cerevisiae S288c
rpl501	Schizosaccharomyces pombe 972h-
rpl502	Schizosaccharomyces pombe 972h-
rpl5	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.