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Gene Review

rpl5  -  ribosomal protein L5

Xenopus (Silurana) tropicalis

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Disease relevance of rpl5


High impact information on rpl5


Biological context of rpl5


Anatomical context of rpl5

  • In contrast, microinjected somatic-type 5S rRNA predominantly interacts with ribosomal protein L5 to form 5S RNPs, which are precursors to ribosome assembly [9].

Analytical, diagnostic and therapeutic context of rpl5


  1. Analysis of the binding of Xenopus ribosomal protein L5 to oocyte 5 S rRNA. The major determinants of recognition are located in helix III-loop C. Scripture, J.B., Huber, P.W. J. Biol. Chem. (1995) [Pubmed]
  2. A feedback loop coupling 5 S rRNA synthesis to accumulation of a ribosomal protein. Pittman, R.H., Andrews, M.T., Setzer, D.R. J. Biol. Chem. (1999) [Pubmed]
  3. Use of the cytotoxic nuclease alpha-sarcin to identify the binding site on eukaryotic 5 S ribosomal ribonucleic acid for the ribosomal protein L5. Huber, P.W., Wool, I.G. J. Biol. Chem. (1986) [Pubmed]
  4. The structure of helix III in Xenopus oocyte 5 S rRNA: an RNA stem containing a two-nucleotide bulge. Huber, P.W., Rife, J.P., Moore, P.B. J. Mol. Biol. (2001) [Pubmed]
  5. A role for ribosomal protein L5 in the nuclear import of 5S rRNA in Xenopus oocytes. Murdoch, K.J., Allison, L.A. Exp. Cell Res. (1996) [Pubmed]
  6. RNA-protein interactions of stored 5S RNA with TFIIIA and ribosomal protein L5 during Xenopus oogenesis. Allison, L.A., Romaniuk, P.J., Bakken, A.H. Dev. Biol. (1991) [Pubmed]
  7. A rice (Oryza sativa L.) cDNA encodes a protein sequence homologous to the eukaryotic ribosomal 5S RNA-binding protein. Kim, J.K., Wu, R. Plant Mol. Biol. (1993) [Pubmed]
  8. Nucleoskeleton and nucleo-cytoplasmic transport in oocytes and early development of Xenopus laevis. Rudt, F., Firmbach-Kraft, I., Petersen, M., Pieler, T., Stick, R. Int. J. Dev. Biol. (1996) [Pubmed]
  9. Differential binding of oocyte-type and somatic-type 5S rRNA to TFIIIA and ribosomal protein L5 in Xenopus oocytes: specialization for storage versus mobilization. Allison, L.A., North, M.T., Neville, L.A. Dev. Biol. (1995) [Pubmed]
  10. Mutual induced fit binding of Xenopus ribosomal protein L5 to 5S rRNA. DiNitto, J.P., Huber, P.W. J. Mol. Biol. (2003) [Pubmed]
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