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Gene Review

mpx  -  myeloid-specific peroxidase

Danio rerio

Synonyms: SO:0000704, fj80f04, mpo, wu:fj80f04
 
 
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High impact information on mpx

  • Studies in embryos after tail transection demonstrated that mpx- and peroxidase-expressing cells were mobile and localized to a site of inflammation, indicating functional capability of these embryonic granulocytes [1].
  • Comparison of hemoglobinized cell distribution, mpx gene expression, and myeloperoxidase histochemistry in wild-type and mutant embryos confirmed that the latter reliably identified a population of myeloid cells [1].
  • Granulocytic cells expressing zebrafish mpo were first evident at 18 hours after fertilization (hpf) in the posterior intermediate cell mass (ICM) and on the anterior yolk sac by 20 hpf [2].

References

  1. Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish. Lieschke, G.J., Oates, A.C., Crowhurst, M.O., Ward, A.C., Layton, J.E. Blood (2001) [Pubmed]
  2. Myelopoiesis in the zebrafish, Danio rerio. Bennett, C.M., Kanki, J.P., Rhodes, J., Liu, T.X., Paw, B.H., Kieran, M.W., Langenau, D.M., Delahaye-Brown, A., Zon, L.I., Fleming, M.D., Look, A.T. Blood (2001) [Pubmed]
 
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