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Gene Review:

Map4 - microtubule-associated protein 4

Rattus norvegicus

Synonyms: MAP-4, Microtubule-associated protein 4

Webster, D.R. et al., Yang, H.J. et al.

Webster, Bratcher,

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High impact information on LOC367171

Finally, it was discovered that cardiomyocyte MAP4 associated with drug- and cold-stable microtubules in early neonatal myocytes [1].
This result suggests that MAP-4 and drebrin may be involved in the antidepressant like effects of desipramine and fluoxetine [2].

Biological context of LOC367171

Up-regulation of microtubule-associated protein 4 and drebrin A mRNA expression by antidepressants in rat hippocampus following chronic stress [2].

Analytical, diagnostic and therapeutic context of LOC367171

In the present study, both immunofluorescence and western blotting methods were used to monitor MAP4 protein expression levels in the developing heart [1].

References

Developmental regulation of cardiac MAP4 protein expression. Webster, D.R., Bratcher, J.M. Cell Motil. Cytoskeleton (2006) [Pubmed]
Up-regulation of microtubule-associated protein 4 and drebrin A mRNA expression by antidepressants in rat hippocampus following chronic stress. Yang, H.J., Li, Y.F., Zhang, H.T., Zhang, F.Q., Zhao, N., Gong, Z.H., Luo, Z.P. Neurosci. Lett. (2003) [Pubmed]

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