Gene Review:
Dbn1 - drebrin 1
Rattus norvegicus
Synonyms:
Developmentally-regulated brain protein, Drebrin
- Antisense knockdown of drebrin A, a dendritic spine protein, causes stronger preference, impaired pre-pulse inhibition, and an increased sensitivity to psychostimulant. Kobayashi, R., Sekino, Y., Shirao, T., Tanaka, S., Ogura, T., Inada, K., Saji, M. Neurosci. Res. (2004)
- Modulatory role of drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex. Hayashi, K., Ishikawa, R., Ye, L.H., He, X.L., Takata, K., Kohama, K., Shirao, T. J. Neurosci. (1996)
- Golgi vesicle proteins are linked to the assembly of an actin complex defined by mAbp1. Fucini, R.V., Chen, J.L., Sharma, C., Kessels, M.M., Stamnes, M. Mol. Biol. Cell (2002)
- Overexpression of drebrin A in immature neurons induces the accumulation of F-actin and PSD-95 into dendritic filopodia, and the formation of large abnormal protrusions. Mizui, T., Takahashi, H., Sekino, Y., Shirao, T. Mol. Cell. Neurosci. (2005)
- Drebrin, a development-associated brain protein from rat embryo, causes the dissociation of tropomyosin from actin filaments. Ishikawa, R., Hayashi, K., Shirao, T., Xue, Y., Takagi, T., Sasaki, Y., Kohama, K. J. Biol. Chem. (1994)
- Effect of a neuron-specific actin-binding protein, drebrin A, on cell-substratum adhesion. Ikeda, K., Shirao, T., Toda, M., Asada, H., Toya, S., Uyemura, K. Neurosci. Lett. (1995)
- Up-regulation of microtubule-associated protein 4 and drebrin A mRNA expression by antidepressants in rat hippocampus following chronic stress. Yang, H.J., Li, Y.F., Zhang, H.T., Zhang, F.Q., Zhao, N., Gong, Z.H., Luo, Z.P. Neurosci. Lett. (2003)
- Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis. Takahashi, H., Sekino, Y., Tanaka, S., Mizui, T., Kishi, S., Shirao, T. J. Neurosci. (2003)
- Overexpression of drebrin A in immature neurons induces the accumulation of F-actin and PSD-95 into dendritic filopodia, and the formation of large abnormal protrusions. Mizui, T., Takahashi, H., Sekino, Y., Shirao, T. Mol. Cell. Neurosci. (2005)
- Inhibition by drebrin of the actin-bundling activity of brain fascin, a protein localized in filopodia of growth cones. Sasaki, Y., Hayashi, K., Shirao, T., Ishikawa, R., Kohama, K. J. Neurochem. (1996)
- Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses. Aoki, C., Sekino, Y., Hanamura, K., Fujisawa, S., Mahadomrongkul, V., Ren, Y., Shirao, T. J. Comp. Neurol. (2005)
- Temporal aspects of spatial task performance during intermittent hypoxia in the rat: evidence for neurogenesis. Gozal, D., Row, B.W., Gozal, E., Kheirandish, L., Neville, J.J., Brittian, K.R., Sachleben, L.R., Guo, S.Z. Eur. J. Neurosci. (2003)
- Rapid conversion of drebrin isoforms during synapse formation in primary culture of cortical neurons. Hayashi, K., Suzuki, K., Shirao, T. Brain Res. Dev. Brain Res. (1998)