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Gene Review:

Mup21 - major urinary protein 21

Mus musculus

Synonyms: Gm11208, Mup, Mup26, OTTMUSG00000000231, bM64F17.1, ...

al-Shawi, R. et al., Rodriguez, M. et al., Novikov, S.N.

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Disease relevance of OTTMUSG00000000231

A transgene consisting of a Mup promoter fused to a Herpes simplex virus thymidine kinase reporter sequence also showed sexual dimorphism, although to a lesser degree [1].

High impact information on OTTMUSG00000000231

Coordinated expression of the genes Gus and Mup as a potential basis of the functional activity of the androgen-dependent pheromones of the house mouse (Mus musculus L.) [2].

Associations of OTTMUSG00000000231 with chemical compounds

Two Mup-alpha 2u-globulin hybrid transgenes with different Mup gene promoters showed sexually dimorphic expression, and their expression in females increased to male levels upon testosterone treatment [1].

Analytical, diagnostic and therapeutic context of OTTMUSG00000000231

Silent and expressed sister Mup genes are located within distinct chromatin domains: analysis by pulsed-field gel electrophoresis and polymerase chain reaction-supplemented DNase I digestion [3].

References

Sexual dimorphism and growth hormone regulation of a hybrid gene in transgenic mice. al-Shawi, R., Wallace, H., Harrison, S., Jones, C., Johnson, D., Bishop, J.O. Mol. Endocrinol. (1992) [Pubmed]
Coordinated expression of the genes Gus and Mup as a potential basis of the functional activity of the androgen-dependent pheromones of the house mouse (Mus musculus L.). Novikov, S.N. Dokl. Biol. Sci. (2003) [Pubmed]
Silent and expressed sister Mup genes are located within distinct chromatin domains: analysis by pulsed-field gel electrophoresis and polymerase chain reaction-supplemented DNase I digestion. Rodriguez, M., Derman, E. Mol. Cell. Biol. (1992) [Pubmed]

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