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Gene Review

sti  -  sticky

Drosophila melanogaster

Synonyms: CG10522, CIT-K, Citron K, DCK, Dmel\CG10522, ...
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High impact information on sti

  • RNA interference-mediated silencing of sti in cultured cells causes them to become multinucleate [1].
  • Here, we report the identification and analysis of a novel Drosophila gene, sticky (sti), essential for cytokinesis in all fly proliferating tissues. sti encodes the Drosophila orthologue of the mammalian Citron kinase [1].
  • Here we report that the Drosophila citron gene encodes an essential effector kinase of Pbl-RhoA signalling in vivo [2].
  • Strong genetic interactions were observed between citron and pbl alleles and constructs [2].
  • Phenotypic analysis of mutants showed that citron is required for cytokinesis in every tissue examined, with mutant cells exhibiting multinucleate and hyperploid phenotypes [2].

Biological context of sti


Other interactions of sti


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