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Gene Review:

LOC395224 - adipocyte fatty acid binding protein

Gallus gallus

Wang, Q. et al., Matsubara, Y. et al., Wang, Q. et al.

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High impact information on LOC395224

Identification of single nucleotide polymorphism of adipocyte fatty acid-binding protein gene and its association with fatness traits in the chicken [1].
The rapid differentiation of cells to mature adipocytes in this culture system was verified by observed increases in adipocyte fatty acid-binding protein (aP2) expression, glycerol-3-phosphate dehydrogenase (GPDH) activity and intracellular triglyceride accumulation [2].
PCR primers were designed according to mammalian A-FABP gene sequence to amplify partial cDNA of A-FABP gene from chicken adipose tissues, and the full length of the gene was cloned by 5'RACE and 3'RACE [3].

Analytical, diagnostic and therapeutic context of LOC395224

RT-PCR and Northern blot analysis indicated that the chicken A-FABP gene, similar to that of the mammal, is only expressed in fat tissues [3].

References

Identification of single nucleotide polymorphism of adipocyte fatty acid-binding protein gene and its association with fatness traits in the chicken. Wang, Q., Li, H., Li, N., Leng, L., Wang, Y., Tang, Z. Poult. Sci. (2006) [Pubmed]
Changes in mRNA expression of regulatory factors involved in adipocyte differentiation during fatty acid induced adipogenesis in chicken. Matsubara, Y., Sato, K., Ishii, H., Akiba, Y. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. (2005) [Pubmed]
Cloning and characterization of chicken adipocyte fatty acid binding protein gene. Wang, Q., Li, H., Li, N., Gu, Z., Wang, Y. Anim. Biotechnol. (2004) [Pubmed]

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