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Gene Review

TSN  -  translin

Gallus gallus

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High impact information on TSN

  • Here we show that Translin, a novel single-stranded DNA end binding protein, forms a ring-shaped structure conserved throughout evolution and that this structure is responsible for its DNA binding activity [1].
  • Translin is a DNA binding protein which specifically binds to consensus sequences at breakpoint junctions of chromosomal translocations in many cases of lymphoid malignancies [2].
  • Levels of 50 ppm of neomycin and 20 ppm of polymixin improved the iron milk tube method when compared to the TSN (tryptone-sulfite-neomycin) agar plate method [3].

Biological context of TSN

  • Genomic structure and chromosomal localization of the gene encoding translin, a recombination hotspot binding protein [4].


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