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Gene Review:

GABRE - gamma-aminobutyric acid (GABA) A receptor,...

Gallus gallus

Kazula, A. et al., Koga, Y. et al., Kazula, A. et al., Enomoto , K. et al.

Enomoto , Kataoka, Hirota,

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High impact information on LOC396173

To clarify the relationship between creatine function and GABA receptors, the i.c.v. co-injection of creatine with picrotoxin, a GABA-A receptor antagonist, or CGP54626, a GABA-B receptor antagonist, was investigated in experiments 3 and 4 [1].
Systemic or intravitreal administration of muscimol, a GABA-A receptor agonist, to light-exposed chicks at the beginning of the dark phase of the light/dark cycle increased retinal melatonin levels and the activity of serotonin N-acetyltransferase (NAT), a key regulatory enzyme of the melatonin biosynthetic pathway [2].
Semiquantitative analysis of the expression of GABA-A receptor subunits in the developing embryonic chick brain stem [3].
The actions of both muscimol and baclofen were antagonized by picrotoxin and bicuculline (two GABA-A receptor blockers), whereas the effect of baclofen was not changed by a selective GABA-B receptor blocker, CGP 35,348 [4].

References

Brain creatine functions to attenuate acute stress responses through GABAnergic system in chicks. Koga, Y., Takahashi, H., Oikawa, D., Tachibana, T., Denbow, D.M., Furuse, M. Neuroscience (2005) [Pubmed]
Regulation of melatonin and dopamine biosynthesis in chick retina: the role of GABA. Kazula, A., Nowak, J.Z., Iuvone, P.M. Vis. Neurosci. (1993) [Pubmed]
Semiquantitative analysis of the expression of GABA-A receptor subunits in the developing embryonic chick brain stem. Enomoto , K., Kataoka, H., Hirota, A. Jpn. J. Physiol. (2001) [Pubmed]
The role of GABA-ergic signal in the regulation of melatonin biosynthesis in vertebrate retina. Kazula, A., Nowak, J.Z. Polish journal of pharmacology and pharmacy. (1992) [Pubmed]

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