Chemical Compound Review:
muscimol 5-(aminomethyl)-1,2-oxazol-3- one
Synonyms:
Agarine, Pantherin, Agarin, Pantherine, Lopac-G-019, ...
- Improvement in tardive dyskinesia after muscimol therapy. Tamminga, C.A., Crayton, J.W., Chase, T.N. Arch. Gen. Psychiatry (1979)
- The rat ventromedial thalamic nucleus and motor control: role of N-methyl-D-aspartate-mediated excitation, GABAergic inhibition, and muscarinic transmission. Klockgether, T., Schwarz, M., Turski, L., Sontag, K.H. J. Neurosci. (1986)
- Postural and anticonvulsant effects of inhibition of the rat subthalamic nucleus. Dybdal, D., Gale, K. J. Neurosci. (2000)
- In vivo studies of GABAergic effects in experimental hepatic encephalopathy. Rzepczynski, D., Zieve, L., Lindblad, S., LaFontaine, D. Hepatology (1986)
- Purinergic regulation of food intake. Levine, A.S., Morley, J.E. Science (1982)
- Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study. Klitenick, M.A., DeWitte, P., Kalivas, P.W. J. Neurosci. (1992)
- Huntington's disease: treatment with muscimol, a GABA-mimetic drug. Shoulson, I., Goldblatt, D., Charlton, M., Joynt, R.J. Ann. Neurol. (1978)
- The amygdala modulates memory consolidation of fear-motivated inhibitory avoidance learning but not classical fear conditioning. Wilensky, A.E., Schafe, G.E., LeDoux, J.E. J. Neurosci. (2000)
- GABAergic modulation of descending inhibitory systems from the rostral ventromedial medulla (RVM). Dose-response analysis of nociception and neurological deficits. Gilbert, A.K., Franklin, K.B. Pain (2001)
- GABA-mediated control of rat neostriatal tyrosine hydroxylase revealed by intranigral muscimol. Gale, K.N., Guidotti, A. Nature (1976)
- Anticipatory activity in primary motor cortex codes memorized movement sequences. Lu, X., Ashe, J. Neuron (2005)
- GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Marty, S., Berninger, B., Carroll, P., Thoenen, H. Neuron (1996)
- Central action of gamma-aminobutyric acid ligands to alter basal water and electrolyte absorption in the rat ileum. Fogel, R., Kaplan, R.B., Arbit, E. Gastroenterology (1985)
- Excitatory versus inhibitory GABA as a divergence point in steroid-mediated sexual differentiation of the brain. Auger, A.P., Perrot-Sinal, T.S., McCarthy, M.M. Proc. Natl. Acad. Sci. U.S.A. (2001)
- delta-Aminolevulinic acid: influences on synaptic GABA receptor binding may explain CNS symptoms of porphyria. Müller, W.E., Snyder, S.H. Ann. Neurol. (1977)
- Inhibition by gamma-amino-n-butyric acid and baclofen of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Tatsuta, M., Iishi, H., Baba, M., Nakaizumi, A., Ichii, M., Taniguchi, H. Cancer Res. (1990)
- Comparison of interactions of [3H]muscimol, t-butylbicyclophosphoro[35S]thionate, and [3H]flunitrazepam with cloned gamma-aminobutyric acidA receptors of the alpha 1 beta 2 and alpha 1 beta 2 gamma 2 subtypes. Pregenzer, J.F., Im, W.B., Carter, D.B., Thomsen, D.R. Mol. Pharmacol. (1993)
- Stimulation of prolactin and growth hormone secretion by muscimol, a gamma-aminobutyric acid agonist. Tamminga, C.A., Neophytides, A., Chase, T.N., Frohman, L.A. J. Clin. Endocrinol. Metab. (1978)
- Effects of GABAergic agonists and antagonists on various ethanol-induced behavioral changes. Liljequist, S., Engel, J. Psychopharmacology (Berl.) (1982)
- cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes. Heuschneider, G., Schwartz, R.D. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Protein kinase C and cAMP-dependent protein kinase phosphorylate the beta subunit of the purified gamma-aminobutyric acid A receptor. Browning, M.D., Bureau, M., Dudek, E.M., Olsen, R.W. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Antihypertensive effect of the GABA receptor agonist muscimol in spontaneously hypertensive rats. Role of the sympathoadrenal axis. Unger, T., Becker, H., Dietz, R., Ganten, D., Lang, R.E., Rettig, R., Schömig, A., Schwab, N.A. Circ. Res. (1984)
- Muscimol acts in dorsomedial but not paraventricular hypothalamic nucleus to suppress cardiovascular effects of stress. Stotz-Potter, E.H., Willis, L.R., DiMicco, J.A. J. Neurosci. (1996)
- [35S]-t-butylbicyclophosphorothionate binding sites are constituents of the gamma-aminobutyric acid benzodiazepine receptor complex. Supavilai, P., Karobath, M. J. Neurosci. (1984)
- Behavioral and neurochemical differentiation of specific projections in the septal-hippocampal cholinergic pathway of the rat. Blaker, W.D., Peruzzi, G., Costa, E. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Neural plasticity without postsynaptic action potentials: less-active inputs become dominant when kitten visual cortical cells are pharmacologically inhibited. Reiter, H.O., Stryker, M.P. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor. Chen, R., Belelli, D., Lambert, J.J., Peters, J.A., Reyes, A., Lan, N.C. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Mechanisms by which diazepam, muscimol, and other drugs change the content of cGMP in cerebellar cortex. Biggio, G., Brodie, B.B., Costa, E., Guidotti, A. Proc. Natl. Acad. Sci. U.S.A. (1977)
- Effects of gamma-aminobutyric acid on skate retinal horizontal cells: evidence for an electrogenic uptake mechanism. Malchow, R.P., Ripps, H. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization. Whatley, V.J., Mihic, S.J., Allan, A.M., McQuilkin, S.J., Harris, R.A. J. Biol. Chem. (1994)
- Lidocaine and muscimol microinjections in subthalamic nucleus reverse Parkinsonian symptoms. Levy, R., Lang, A.E., Dostrovsky, J.O., Pahapill, P., Romas, J., Saint-Cyr, J., Hutchison, W.D., Lozano, A.M. Brain (2001)
- Effect of muscimol on glucose-stimulated somatostatin and insulin release from the isolated, perfused rat pancreas. Robbins, M.S., Grouse, L.H., Sorenson, R.L., Elde, R.P. Diabetes (1981)
- ATP-Sensitive K+ Channels Regulate the Release of GABA in the Ventromedial Hypothalamus During Hypoglycemia. Chan, O., Lawson, M., Zhu, W., Beverly, J.L., Sherwin, R.S. Diabetes (2007)
- Regulation of somatodendritic GABAA receptor channels in rat hippocampal neurons: evidence for a role of the small GTPase Rac1. Meyer, D.K., Olenik, C., Hofmann, F., Barth, H., Leemhuis, J., Brünig, I., Aktories, K., Nörenberg, W. J. Neurosci. (2000)
- The influence of gamma-aminobutyric acid on hormone release by the mouse and rat endocrine pancreas. Gilon, P., Bertrand, G., Loubatières-Mariani, M.M., Remacle, C., Henquin, J.C. Endocrinology (1991)
- Duality of glutamatergic and GABAergic control of pulsatile GnRH secretion by rat hypothalamic explants: I. Effects of antisense oligodeoxynucleotides using explants including or excluding the preoptic area. Bourguignon, J.P., Gérard, A., Purnelle, G., Czajkowski, V., Yamanaka, C., Lemaître, M., Rigo, J.M., Moonen, G., Franchimont, P. J. Neuroendocrinol. (1997)
- Early Activation of Extracellular Signal-Regulated Kinase Signaling Pathway in the Hippocampus is Required for Short-Term Memory Formation of a Fear-Motivated Learning. Igaz, L.M., Winograd, M., Cammarota, M., Izquierdo, L.A., Alonso, M., Izquierdo, I., Medina, J.H. Cell. Mol. Neurobiol. (2006)
- Effect of dopamine on amylase secretion from guinea pig pancreatic acinar cells in vitro. Xue, B.G., Hernandez, D.E. Life Sci. (1989)
- Bilateral alterations in local cerebral glucose utilization following intranigral application of the GABAergic agonist muscimol. Dermon, C.R., Pizarro, P., Georgopoulos, P., Savaki, H.E. J. Neurosci. (1990)