Gene Review:
LOC397881 - cardiac myosin heavy chain
Xenopus laevis
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High impact information on LOC397881
- RT-PCR analysis determined that CMHC transcripts are present in the cardiac mesoderm at state 13, demonstrating that muscle-specific gene expression in the primitive myocardium has begun by the early neurula stage, approximately 30 h before the heart beat begins [1].
- CMHC gene expression was also detected in skeletal muscle: RT-PCR analysis determined that CMHC transcripts are transiently expressed in the somite during the initial phases of skeletal muscle differentiation [1].
- Furthermore, CMHC mRNAs are expressed in a subset of head muscles of the feeding tadpole [1].
- The earliest CMHC gene transcripts can be detected in the heart using whole-mount in situ hybridization is early tailbud stage 28, which coincides with the onset of heart tube morphogenesis [1].
References
- Cardiac myosin heavy chain expression during heart development in Xenopus laevis. Cox, W.G., Neff, A.W. Differentiation (1995) [Pubmed]
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