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Gene Review:

agtr1-a - angiotensin 2 receptor, type 1

Xenopus laevis

Bergsma, D.J. et al., Inestrosa, N.C. et al., Czirják, G. et al., Ji, H. et al.

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High impact information on MGC68752

Similarly, in oocytes coexpressing TASK and ATla angiotensin II receptor, angiotensin II inhibited the TASK current [1].
Radioligand binding studies with the cloned receptor expressed in COS cells indicated that it is an angiotensin II receptor that possesses pharmacological properties distinct from those of the two known mammalian receptor subtypes, AT1 and AT2 [2].
Expression of size-selected messenger RNA encoding the brain and adrenal gland angiotensin-II receptor in Xenopus laevis oocytes [3].

Analytical, diagnostic and therapeutic context of MGC68752

Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor [4].

References

TASK (TWIK-related acid-sensitive K+ channel) is expressed in glomerulosa cells of rat adrenal cortex and inhibited by angiotensin II. Czirják, G., Fischer, T., Spät, A., Lesage, F., Enyedi, P. Mol. Endocrinol. (2000) [Pubmed]
Isolation and expression of a novel angiotensin II receptor from Xenopus laevis heart. Bergsma, D.J., Ellis, C., Nuthulaganti, P.R., Nambi, P., Scaife, K., Kumar, C., Aiyar, N. Mol. Pharmacol. (1993) [Pubmed]
Expression of size-selected messenger RNA encoding the brain and adrenal gland angiotensin-II receptor in Xenopus laevis oocytes. Inestrosa, N.C., Cross, D. Arch. Biol. Med. Exp. (1988) [Pubmed]
Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor. Ji, H., Sandberg, K., Zhang, Y., Catt, K.J. Biochem. Biophys. Res. Commun. (1993) [Pubmed]

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