Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Nopp140 - CG7421 gene product from transcript CG7421-RE

Drosophila melanogaster

Synonyms: CG7421, DmNopp140, Dmel\CG7421, Nopp- 140, nopp140

Waggener, J.M. et al., McCain, J. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Nopp140

DmNopp140 (654 residues) is the sequence homolog of vertebrate Nopp140 [1].
The Nopp140 gene of Drosophila maps within 79A5 of chromosome 3 [1].
In HeLa cells, DmNopp140-RGG localizes to intact nucleoli, whereas DmNopp140 partitions HeLa nucleoli into phase-light and phase-dark regions [1].
DmNopp140-RGG (688 residues) is identical to DmNopp140 throughout its first 551 residues, but its carboxy terminus contains a glycine/arginine-rich domain that is often found in RNA-binding proteins such as vertebrate nucleolin [1].
Specifically, we wanted to test whether the quiescent oocyte nucleus stored maternal Nopp140 and then to determine precisely when nucleoli formed during embryogenesis [2].

References

Two splice variants of Nopp140 in Drosophila melanogaster. Waggener, J.M., DiMario, P.J. Mol. Biol. Cell (2002) [Pubmed]
Tracking nucleolar dynamics with GFP-Nopp140 during Drosophila oogenesis and embryogenesis. McCain, J., Danzy, L., Hamdi, A., Dellafosse, O., DiMario, P. Cell Tissue Res. (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share