Psychiatry related information on mub

• Mushroom bodies suppress locomotor activity in Drosophila melanogaster [1].

High impact information on mub

• Mushroom bodies, Ca(2+) oscillations, and the memory gene amnesiac [2].
• Mushroom bodies (MBs) are symmetrically paired neuropils in the insect brain that are of critical importance for associative olfactory learning and memory [3].
• Here, we show that the voltage-dependent K(+) currents expressed by the intrinsic neurons of the Mushroom bodies are upward-modulated by compounds that remove sterols from the plasma membrane [4].
• Null mutants of the mub gene do not exhibit a visible mutant phenotype [5].
• The mub gene encodes a protein containing three KH domains and is expressed in the mushroom bodies of Drosophila melanogaster [5].

Biological context of mub

• From one of the enhancer trap lines, which shows specific lacZ expression in the CNS and prothoracic part of the ring gland, the mub gene was cloned [5].

References