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Gene Review

nrp2a  -  neuropilin 2a

Danio rerio

Synonyms: SO:0000704
 
 
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High impact information on nrp2a

  • Knockdown of nrp1a, nrp1b, and nrp2a resulted in improper arteriovenous connections and irregular intersegmental vessel patterning, indicating that these Nrps function in the same process [1].
  • Subsequently, we have isolated three other full-length neuropilin genes (nrp1b, nrp2a, and nrp2b) and find that they map to independent zebrafish linkage groups [2].
  • Zebrafish nrp2a is expressed in telencephalon, anterior pituitary, oculomotor and trochlear motor neurons, cells along the supra-optic and posterior commissures, hindbrain rhombomere 1, hindbrain neurons, cranial NCCs and sclerotome [3].

References

  1. Zebrafish neuropilins are differentially expressed and interact with vascular endothelial growth factor during embryonic vascular development. Martyn, U., Schulte-Merker, S. Dev. Dyn. (2004) [Pubmed]
  2. Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish. Bovenkamp, D.E., Goishi, K., Bahary, N., Davidson, A.J., Zhou, Y., Becker, T., Becker, C.G., Zon, L.I., Klagsbrun, M. Gene Expr. Patterns (2004) [Pubmed]
  3. Cloning and embryonic expression of zebrafish neuropilin genes. Yu, H.H., Houart, C., Moens, C.B. Gene Expr. Patterns (2004) [Pubmed]
 
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