Gene Review:
Nrg2 - neuregulin 2
Rattus norvegicus
Synonyms:
NTAK_alpha2a, Ntak, Pro-NRG2, Pro-neuregulin-2, membrane-bound isoform
- Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Chang, H., Riese, D.J., Gilbert, W., Stern, D.F., McMahan, U.J. Nature (1997)
- Neuregulin-2 is synthesized by motor neurons and terminal Schwann cells and activates acetylcholine receptor transcription in muscle cells expressing ErbB4. Rimer, M., Prieto, A.L., Weber, J.L., Colasante, C., Ponomareva, O., Fromm, L., Schwab, M.H., Lai, C., Burden, S.J. Mol. Cell. Neurosci. (2004)
- Neuregulin-2 is developmentally regulated and targeted to dendrites of central neurons. Longart, M., Liu, Y., Karavanova, I., Buonanno, A. J. Comp. Neurol. (2004)
- Stimulation of acetylcholine receptor transcription by neuregulin-2 requires an N-box response element and is regulated by alternative splicing. Ponomareva, O.N., Ma, H., Dakour, R., Raabe, T.D., Lai, C., Rimer, M. Neuroscience (2005)
- Reduced Aph-1b expression causes tissue- and substrate-specific changes in gamma-secretase activity in rats with a complex phenotype. Coolen, M.W., van Loo, K.M., van Bakel, N.N., Ellenbroek, B.A., Cools, A.R., Martens, G.J. FASEB J. (2006)