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Gene Review

RN18S1  -  18S ribosomal RNA

Bos taurus

 
 
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Disease relevance of LOC493779

 

High impact information on LOC493779

  • The ratio of CYP17 messenger RNA (mRNA) to 18S ribosomal RNA was also significantly higher in fetal adrenals ofthe N-POMC-(1-77)-infused group (49.1+/-4.7) compared with that in either the N-POMC-(1-49)-infused (20.4+/-6.4) or saline-infused (15.2+/-4.4) group [2].
  • There was no difference, however, in the ratios of adrenal CYP11A1 mRNA/3beta-hydroxysteroid dehydrogenase/delta5,delta4-isomerase mRNA and CYP21A1 mRNA/18S ribosomal RNA among the N-POMC-(1-77)-, N-POMC-(1-49)-, and saline-infused groups [2].
  • Sequence comparison search revealed similarity of some isolated fragments to 18s ribosomal RNA, bovine apolipoprotein A-I, bovine mitochondrion DNA, human CGI-79 mRNA, human Ab1-interactor protein, and bovine satellite DNA [3].
  • The 5' noncoding region does not contain an AUG before the initiator codon and contains two potential regions that could base-pair with sequences near the 3' terminus of 18S ribosomal RNA [4].
  • Molecular and phylogenetic analyses at the 18S ribosomal RNA, heat shock protein 70, and actin gene loci demonstrate C. suis to be genetically distinct from all known species and genotypes of Cryptosporidium, and thus is named as Cryptosporidium suis [5].
 

Biological context of LOC493779

  • The 18S ribosomal RNA and merozoite-piroplasm surface protein-encoding genes display a wider genetic variation within the T. buffeli group than between well defined species like T. annulata and T. parva [6].
 

Analytical, diagnostic and therapeutic context of LOC493779

References

  1. The detection of a novel type of Cryptosporidium andersoni oocyst in cattle in Japan. Matsubayashi, M., Kimata, I., Abe, N., Tani, H., Sasai, K. Parasitol. Res. (2004) [Pubmed]
  2. Infusion of N-proopiomelanocortin-(1-77) increases adrenal weight and messenger ribonucleic acid levels of cytochrome P450 17alpha-hydroxylase in the sheep fetus during late gestation. Ross, J.T., Bennett, H.P., James, S., McMillen, I.C. Endocrinology (2000) [Pubmed]
  3. Comparison by restriction fragment differential display RT-PCR of gene expression pattern in bovine oocytes matured in the presence or absence of fetal calf serum. Rzucidlo, S.J., Gibbons, J., Stice, S.L. Mol. Reprod. Dev. (2001) [Pubmed]
  4. Nucleotide sequence of bovine parathyroid hormone messenger RNA. Weaver, C.A., Gordon, D.F., Kemper, B. Mol. Cell. Endocrinol. (1982) [Pubmed]
  5. Cryptosporidium suis n. sp. (Apicomplexa: Cryptosporidiidae) in pigs (Sus scrofa). Ryan, U.M., Monis, P., Enemark, H.L., Sulaiman, I., Samarasinghe, B., Read, C., Buddle, R., Robertson, I., Zhou, L., Thompson, R.C., Xiao, L. J. Parasitol. (2004) [Pubmed]
  6. The phylogenetic position of the Theileria buffeli group in relation to other Theileria species. Gubbels, M.J., Yin, H., Bai, Q., Liu, G., Nijman, I.J., Jongejan, F. Parasitol. Res. (2002) [Pubmed]
  7. Molecular characterization of a non-Babesia divergens organism causing zoonotic babesiosis in Europe. Herwaldt, B.L., Cacciò, S., Gherlinzoni, F., Aspöck, H., Slemenda, S.B., Piccaluga, P., Martinelli, G., Edelhofer, R., Hollenstein, U., Poletti, G., Pampiglione, S., Löschenberger, K., Tura, S., Pieniazek, N.J. Emerging Infect. Dis. (2003) [Pubmed]
 
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