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Gene Review

EEF1A1  -  eukaryotic translation elongation factor 1...

Pan troglodytes

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High impact information on EEF1A1

  • Ten mouse hybridoma cell lines producing IgG monoclonal antibodies to mycoplasmal elongation factor Tu (EF-Tu) were established [1].
  • A strong splice acceptor site obtained from the exon/intron junction of either the chimpanzee EF1-alpha gene or the human CMV major immediate early gene was placed downstream of the MoMSV packaging signal (Psi), significantly improving the efficiency of transgene expression [2].


  1. Species differentiation of mycoplasmas by EF-Tu specific monoclonal antibodies. Kamla, V., Henrich, B., Hadding, U. J. Immunol. Methods (1992) [Pubmed]
  2. Construction of retroviral vectors with enhanced efficiency of transgene expression. Hahm, S.H., Yi, Y., Lee, D.K., Noh, M.J., Yun, L., Hwang, S., Lee, K.H. J. Virol. Methods (2004) [Pubmed]
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