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PSMC1  -  proteasome (prosome, macropain) 26S...

Bos taurus

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High impact information on PSMC1

  • Inhibition of specific [125I]AII binding was demonstrated in porcine smooth muscle cell (PSMC) suspensions with unlabeled AII and losartan [1].
  • This response was blocked by losartan (10(-6) to 10(-5) mol/L) but not by PD123177 (10(-6) to 10(-5) mol/L) and neither agent stimulated basal release in PSMC [1].


  1. AT1 receptors mediate the release of prostaglandins in porcine smooth muscle cells and rat astrocytes. Leung, K.H., Chang, R.S., Lotti, V.J., Roscoe, W.A., Smith, R.D., Timmermans, P.B., Chiu, A.T. Am. J. Hypertens. (1992) [Pubmed]
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