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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ARL6IP4  -  ADP-ribosylation factor-like 6 interacting...

Homo sapiens

Synonyms: ADP-ribosylation factor-like protein 6-interacting protein 4, ARL-6-interacting protein 4, Aip-4, HSP-975, HSVI-binding protein, ...
 
 
 
 
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High impact information on ARL6IP4

  • Based on the presence of many nuclear localizing signals and a similarity to RNA splicing proteins, SR-25 is strongly suggested to be a nuclear protein and may contribute to RNA splicing [1].
  • Deduced amino acid sequences of mouse SR-25 and human SR-25 showed 77.7% identity [1].
  • We cloned a full-length mouse cDNA and its human homologue encoding a novel protein designated as "SR-25." In Northern blot analysis, SR-25 mRNA was expressed in all organs tested, and relatively abundant in testis and thymus [1].
  • SR-25 has a serine-arginine repeat (SR repeat) and two types of amino acid clusters: a serine cluster and a highly basic cluster [1].
 

Analytical, diagnostic and therapeutic context of ARL6IP4

References

  1. Molecular cloning and expression analysis of a putative nuclear protein, SR-25. Sasahara, K., Yamaoka, T., Moritani, M., Tanaka, M., Iwahana, H., Yoshimoto, K., Miyagawa, J., Kuroda, Y., Itakura, M. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
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