Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

PTGIR - prostaglandin I2 (prostacyclin) receptor (IP)

Bos taurus

Lerner, R.W. et al., Zucker, T.P. et al.

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High impact information on LOC520278

There was no evidence for transcriptional down-regulation of prostacyclin receptor gene by iloprost [1].
In summary, our results indicate that a prostacyclin receptor is present on the cardiac sarcolemmal membrane, and that PGI2 competes for the same receptor site as PGE2 [2].

References

Tolerance development to antimitogenic actions of prostacyclin but not of prostaglandin E1 in coronary artery smooth muscle cells. Zucker, T.P., Bönisch, D., Hasse, A., Grosser, T., Weber, A.A., Schrör, K. Eur. J. Pharmacol. (1998) [Pubmed]
[3H]iloprost and prostaglandin E2 compete for the same receptor site on cardiac sarcolemmal membranes. Lerner, R.W., Lopaschuk, G.D., Catena, R.C., Olley, P.M. Biochim. Biophys. Acta (1992) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

PTGIR	Canis lupus familiaris
ptgir	Danio rerio
PTGIR	Homo sapiens
PTGIR	Macaca mulatta
Ptgir	Mus musculus
PTGIR	Pan troglodytes
Ptgir	Rattus norvegicus
ptgir	Xenopus (Silurana) tropicalis

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