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Gene Review

PLK1  -  polo-like kinase 1

Bos taurus

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High impact information on PLK1

  • The results, which indicate that PM is a good substrate for brain PL kinase, are consistent with the proposed role of intracellular phosphorylation in the uptake of vitamin B-6 brain tissue [1].
  • About 65% of the recovered PL kinase activity of crude mitochondria is released from synaptosomal fraction after hypoosmotic treatment [2].
  • PL kinase activity has been determined in primary and secondary subcellular fractions of ox retina [2].

Analytical, diagnostic and therapeutic context of PLK1


  1. Activity of pyridoxamine as a substrate for brain pyridoxal kinase. Gregory, J.F. J. Neurochem. (1980) [Pubmed]
  2. Subcellular distribution of pyridoxal kinase in ox retina. Macaione, S., Di Giorgio, R.M., De Luca, G. Ital. J. Biochem. (1976) [Pubmed]
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