Gene Review:
CDC5 - polo kinase CDC5
Saccharomyces cerevisiae S288c
Synonyms:
Cell cycle serine/threonine-protein kinase CDC5/MSD2, MSD2, PKX2, YM8270.03C, YMR001C
Burns,
Ohi,
Krainer,
Gould,
Shou,
Azzam,
Chen,
Huddleston,
Baskerville,
Charbonneau,
Annan,
Carr,
Deshaies,
- Chromosome morphogenesis: condensin-dependent cohesin removal during meiosis. Yu, H.G., Koshland, D. Cell (2005)
- Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Hu, F., Wang, Y., Liu, D., Li, Y., Qin, J., Elledge, S.J. Cell (2001)
- CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Toczyski, D.P., Galgoczy, D.J., Hartwell, L.H. Cell (1997)
- A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Kitada, K., Johnson, A.L., Johnston, L.H., Sugino, A. Mol. Cell. Biol. (1993)
- Mitotic exit network controls the localization of Cdc14 to the spindle pole body in Saccharomyces cerevisiae. Yoshida, S., Asakawa, K., Toh-e, A. Curr. Biol. (2002)
- The Polo-related kinase Cdc5 activates and is destroyed by the mitotic cyclin destruction machinery in S. cerevisiae. Charles, J.F., Jaspersen, S.L., Tinker-Kulberg, R.L., Hwang, L., Szidon, A., Morgan, D.O. Curr. Biol. (1998)
- Evidence that Myb-related CDC5 proteins are required for pre-mRNA splicing. Burns, C.G., Ohi, R., Krainer, A.R., Gould, K.L. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Mad3/BubR1 phosphorylation during spindle checkpoint activation depends on both Polo and Aurora kinases in budding yeast. Rancati, G., Crispo, V., Lucchini, G., Piatti, S. Cell Cycle (2005)
- Polo-like kinase, a novel marker for cellular proliferation. Yuan, J., Hörlin, A., Hock, B., Stutte, H.J., Rübsamen-Waigmann, H., Strebhardt, K. Am. J. Pathol. (1997)
- Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesis. Yoshida, S., Kono, K., Lowery, D.M., Bartolini, S., Yaffe, M.B., Ohya, Y., Pellman, D. Science (2006)
- Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Ohi, M.D., Link, A.J., Ren, L., Jennings, J.L., McDonald, W.H., Gould, K.L. Mol. Cell. Biol. (2002)
- Cell cycle regulation of DNA replication initiator factor Dbf4p. Cheng, L., Collyer, T., Hardy, C.F. Mol. Cell. Biol. (1999)
- Cdc5 influences phosphorylation of Net1 and disassembly of the RENT complex. Shou, W., Azzam, R., Chen, S.L., Huddleston, M.J., Baskerville, C., Charbonneau, H., Annan, R.S., Carr, S.A., Deshaies, R.J. BMC Mol. Biol. (2002)
- In vitro regulation of budding yeast Bfa1/Bub2 GAP activity by Cdc5. Geymonat, M., Spanos, A., Walker, P.A., Johnston, L.H., Sedgwick, S.G. J. Biol. Chem. (2003)
- Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. Sanchez, Y., Bachant, J., Wang, H., Hu, F., Liu, D., Tetzlaff, M., Elledge, S.J. Science (1999)
- Polo kinase controls cell-cycle-dependent transcription by targeting a coactivator protein. Darieva, Z., Bulmer, R., Pic-Taylor, A., Doris, K.S., Geymonat, M., Sedgwick, S.G., Morgan, B.A., Sharrocks, A.D. Nature (2006)
- Essential function of the polo box of Cdc5 in subcellular localization and induction of cytokinetic structures. Song, S., Grenfell, T.Z., Garfield, S., Erikson, R.L., Lee, K.S. Mol. Cell. Biol. (2000)
- Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex. Rudner, A.D., Murray, A.W. J. Cell Biol. (2000)
- Novel functional dissection of the localization-specific roles of budding yeast polo kinase Cdc5p. Park, J.E., Park, C.J., Sakchaisri, K., Karpova, T., Asano, S., McNally, J., Sunwoo, Y., Leem, S.H., Lee, K.S. Mol. Cell. Biol. (2004)
- Cdc5 interacts with the Wee1 kinase in budding yeast. Bartholomew, C.R., Woo, S.H., Chung, Y.S., Jones, C., Hardy, C.F. Mol. Cell. Biol. (2001)