Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

POLD2 - polymerase (DNA directed), delta 2,...

Homo sapiens

Synonyms: DNA polymerase delta subunit 2, DNA polymerase delta subunit p50

Perez, A. et al.

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High impact information on POLD2

The functional activity of the regulatory region of the human POLD2 gene was demonstrated by its ability to drive the expression of a chloramphenicol acetyltransferase reporter gene in COS-7 cells [1].
We have isolated genomic DNA clones covering the gene for the human DNA polymerase delta 50 kDa subunit (POLD2) and its 5'-flanking sequence [1].
The POLD2 gene is composed of 11 exons and is distributed over 10 kb of genomic DNA [1].
The 5'-flanking region of human POLD2 is G+C-rich and does not have a typical TATA box [1].

References

Characterization of the 5'-flanking region of the gene encoding the 50 kDa subunit of human DNA polymerase delta. Perez, A., Leon, A., Lee, M.Y. Biochim. Biophys. Acta (2000) [Pubmed]

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CG12018	Drosophila melanogaster
POLD2	Gallus gallus
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Pold2	Mus musculus
Os03g0128500	Oryza sativa Japonica Group
POLD2	Pan troglodytes
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pold2	Xenopus (Silurana) tropicalis

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