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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

INO80  -  INO80 complex subunit

Homo sapiens

Synonyms: DNA helicase INO80, INO80 complex subunit A, INO80A, INOC1, Ino80, ...
 
 
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Disease relevance of INOC1

  • Small intestinal weight per 100 g of body weight was greater (P less than .001) in inoc poults, but empty weights per length of jejunum and ileum were less (P less than .05) [1].
 

High impact information on INOC1

  • A variety of highly functionalized cis-decalin systems have been prepared by means of the stereoselective transannular Diels-Alder (TADA) reaction of a (Z,E,Z,Z)-tetraene macrolide, and by means of intramolecular nitrile oxide olefin (INOC) or ring-closing metathesis (RCM) annulations to quinic acid derivatives [2].
  • Activities of disaccharidases in the jejunum and ileum of inoc poults were less (P less than .05) than in control poults [1].
  • The jejunal mucosa in inoc poults was thinner, exhibited extensive erosion of villi tips, and had microvilli that seemed to be fused when observed by using scanning electron microscopy [1].

References

  1. Stunting syndrome in turkeys: physical and physiological changes. Angel, C.R., Sell, J.L., Trampel, D.W. Poult. Sci. (1990) [Pubmed]
  2. Toward the synthesis of the antibiotic branimycin: novel approaches to highly substituted cis-decalin systems. Mulzer, J., Castagnolo, D., Felzmann, W., Marchart, S., Pilger, C., Enev, V.S. Chemistry (Weinheim an der Bergstrasse, Germany) (2006) [Pubmed]
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