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Gene Review:

acvr2aa - activin A receptor, type IIAa

Danio rerio

Synonyms: SO:0000704, actr2a, acvr2, acvr2a, wu:fa02e10

Albertson, R.C. et al.

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High impact information on acvr2a

Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development [1].

Biological context of acvr2a

Although ubiquitously expressed as maternal mRNAs and in early embryogenesis, by 24 hr postfertilization (hpf), acvr2a and acvr2b exhibit restricted expression in neural, hindbrain, and neural crest cells (NCCs) [1].

Anatomical context of acvr2a

These studies revealed previously uncharacterized roles for acvr2a and acvr2b in hindbrain and NCC patterning, in NCC derived pharyngeal arch cartilage and joint formation, and in tooth development [1].

References

Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development. Albertson, R.C., Payne-Ferreira, T.L., Postlethwait, J., Yelick, P.C. Dev. Dyn. (2005) [Pubmed]

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AgaP_AGAP000763	Anopheles gambiae str. PEST
ACVR2A	Bos taurus
ACVR2A	Canis lupus familiaris
put	Drosophila melanogaster
ACVR2A	Gallus gallus
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ACVR2A	Macaca mulatta
Acvr2a	Mus musculus
ACVR2A	Pan troglodytes
Acvr2a	Rattus norvegicus
acvr2a	Xenopus (Silurana) tropicalis

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