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Gene Review:

ACVR2A - activin A receptor, type IIA

Bos taurus

Flavin, N. et al., Fazzini, M. et al.

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High impact information on ACVR2

Although these cells showed a similar effect on FS mRNA expression after treatment with activin-A, a soluble form of activin receptor type IIA was unable to inactivate the TGF-beta effect [1].
Cloning of the bovine activin receptor type II gene (ACVR2) and mapping to chromosome 2 (BTA2) [2].
Using PCR analysis of bovine x hamster somatic cell lines, the ACVR2 gene was mapped to syntenic group U17, which has been localised to bovine chromosome 2 [2].
Genotyping a highly polymorphic microsatellite locus, (AT)4(GT)9(AT)11, found within an intron of this gene confirmed the localisation by linking the ACVR2-associated microsatellite to the region of chromosome 2 flanked by CSSM42 and TGLA226 [2].

References

Transforming growth factor beta1 regulates follistatin mRNA expression during in vitro bovine granulosa cell differentiation. Fazzini, M., Vallejo, G., Colman-Lerner, A., Trigo, R., Campo, S., Barañao, J.L., Saragüeta, P.E. J. Cell. Physiol. (2006) [Pubmed]
Cloning of the bovine activin receptor type II gene (ACVR2) and mapping to chromosome 2 (BTA2). Flavin, N., Heriz, A., Monteagudo, L.V., Ennis, S., Martin, F., Barendse, W., Arruga, M.V., Rogers, M. Cytogenet. Cell Genet. (1996) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP000763	Anopheles gambiae str. PEST
ACVR2A	Canis lupus familiaris
acvr2aa	Danio rerio
put	Drosophila melanogaster
ACVR2A	Gallus gallus
ACVR2A	Homo sapiens
ACVR2A	Macaca mulatta
Acvr2a	Mus musculus
ACVR2A	Pan troglodytes
Acvr2a	Rattus norvegicus
acvr2a	Xenopus (Silurana) tropicalis

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