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Gene Review:

PLEKHA4 - pleckstrin homology domain containing,...

Homo sapiens

Synonyms: PEPP-1, PEPP1, PH domain-containing family A member 4, Phosphoinositol 3-phosphate-binding protein 1, Pleckstrin homology domain-containing family A member 4

Geadah, M.W. et al., Smith, M.D. et al., Lee, P.L. et al., Bigbee, W.L. et al., Miki, Y. et al.

Bigbee, Day, Grant, Keohavong, Xi, Zhang, Ness,

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Disease relevance of PLEKHA4

Impact of maternal lifestyle factors on newborn HPRT mutant frequencies and molecular spectrum--initial results from the Prenatal Exposures and Preeclampsia Prevention (PEPP) Study [1].

Psychiatry related information on PLEKHA4

The Pharmacists Educating Patients Program (PEPP) was designed (1) to provide pharmacists with smoking cessation consultation guidelines for patients on nicotine transdermal therapy and (2) to test the effectiveness of these pharmacists' consultation services [2].

High impact information on PLEKHA4

Other organophosphorous inhibitors, such as p-NPEPP and PEPP, were also effective, but a nonphosphorylating analogue of DFP, DMP, was not inhibitory [3].
One of the three polymorphisms, Pro163Leu, is the second proline in a proline cluster (PEPP) in a region separating the SCAN box from the zinc finger motifs [4].

Analytical, diagnostic and therapeutic context of PLEKHA4

A device is described with which the PEPP may be used with the Bird ventilator (mark 7 or 8) during assisted and/or controlled ventilation [5].
PEPP and the Bird ventilator. Application of a positive end expiratory pressure plateau to the Bird ventilator for assisted and controlled ventilation [5].

References

Impact of maternal lifestyle factors on newborn HPRT mutant frequencies and molecular spectrum--initial results from the Prenatal Exposures and Preeclampsia Prevention (PEPP) Study. Bigbee, W.L., Day, R.D., Grant, S.G., Keohavong, P., Xi, L., Zhang, L., Ness, R.B. Mutat. Res. (1999) [Pubmed]
Pharmacist counseling and outcomes of smoking cessation. Smith, M.D., McGhan, W.F., Lauger, G. American pharmacy. (1995) [Pubmed]
The requirement for esterase activation in T cell replacing factor (TRF)-induced IgG production in a human B blastoid cell line. Miki, Y., Kishi, H., Muraguchi, A., Kishimoto, S., Yamamura, Y., Kishimoto, T. J. Immunol. (1982) [Pubmed]
Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. Lee, P.L., Gelbart, T., West, C., Adams, M., Blackstone, R., Beutler, E. Genomics (1997) [Pubmed]
PEPP and the Bird ventilator. Application of a positive end expiratory pressure plateau to the Bird ventilator for assisted and controlled ventilation. Geadah, M.W., Seed, R.F. Anaesthesia. (1976) [Pubmed]

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