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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

dct  -  dopachrome tautomerase

Danio rerio

Synonyms: SO:0000704, TRP-2, trp2, zgc:109860
 
 
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High impact information on dct

  • Expression of melanocyte markers in regenerating kit mutant fins suggests that kit normally acts after mitf and before dct to promote development of the primary kit-dependent melanocytes. kit-dependent and kit-independent melanocytes are also present during fin stripe ontogeny in patterns similar to those observed during regeneration [1].
  • Analysis of expression of dopachrome tautomerase (dct) and microphthalmia (mitfa) suggests that melanophore precursors are specified normally in homozygous tct mutants [2].

References

  1. Zebrafish kit mutation reveals primary and secondary regulation of melanocyte development during fin stripe regeneration. Rawls, J.F., Johnson, S.L. Development (2000) [Pubmed]
  2. Touchtone promotes survival of embryonic melanophores in zebrafish. Cornell, R.A., Yemm, E., Bonde, G., Li, W., d'Alençon, C., Wegman, L., Eisen, J., Zahs, A. Mech. Dev. (2004) [Pubmed]
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