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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

mitfa  -  microphthalmia-associated transcription...

Danio rerio

Synonyms: SO:0000704, nacre, z3A.1
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Disease relevance of mitfa


High impact information on mitfa


Biological context of mitfa


Anatomical context of mitfa


Other interactions of mitfa

  • By transplanting cells between fms mutants and either wild-type or nacre mutant zebrafish, we show that fms acts autonomously to the xanthophore lineage in promoting the striped arrangement of adult melanophores [8].


  1. BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Patton, E.E., Widlund, H.R., Kutok, J.L., Kopani, K.R., Amatruda, J.F., Murphey, R.D., Berghmans, S., Mayhall, E.A., Traver, D., Fletcher, C.D., Aster, J.C., Granter, S.R., Look, A.T., Lee, C., Fisher, D.E., Zon, L.I. Curr. Biol. (2005) [Pubmed]
  2. Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway. Dorsky, R.I., Raible, D.W., Moon, R.T. Genes Dev. (2000) [Pubmed]
  3. Effective targeted gene 'knockdown' in zebrafish. Nasevicius, A., Ekker, S.C. Nat. Genet. (2000) [Pubmed]
  4. The evolution of morphological complexity in zebrafish stripes. Mellgren, E.M., Johnson, S.L. Trends Genet. (2002) [Pubmed]
  5. Transcriptional regulation of mitfa accounts for the sox10 requirement in zebrafish melanophore development. Elworthy, S., Lister, J.A., Carney, T.J., Raible, D.W., Kelsh, R.N. Development (2003) [Pubmed]
  6. Duplicate mitf genes in zebrafish: complementary expression and conservation of melanogenic potential. Lister, J.A., Close, J., Raible, D.W. Dev. Biol. (2001) [Pubmed]
  7. Touchtone promotes survival of embryonic melanophores in zebrafish. Cornell, R.A., Yemm, E., Bonde, G., Li, W., d'Alençon, C., Wegman, L., Eisen, J., Zahs, A. Mech. Dev. (2004) [Pubmed]
  8. Temporal and cellular requirements for Fms signaling during zebrafish adult pigment pattern development. Parichy, D.M., Turner, J.M. Development (2003) [Pubmed]
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