Gene Review:
Dct - dopachrome tautomerase
Mus musculus
Synonyms:
DCT, DT, L-dopachrome Delta-isomerase, L-dopachrome tautomerase, SLATY locus protein, ...
Kawa,
Ito,
Ono,
Asano,
Takano,
Ooka,
Watabe,
Hosaka,
Baba,
Kubota,
Mizoguchi,
Bronte,
Apolloni,
Ronca,
Zamboni,
Overwijk,
Surman,
Restifo,
Zanovello,
Prins,
Bruhn,
Craft,
Lin,
Kim,
Odesa,
Miller,
Liau,
Keverne,
Tüting,
Steitz,
Brück,
Gambotto,
Steinbrink,
DeLeo,
Robbins,
Knop,
Enk,
Collinson,
Quinn,
Hill,
West,
Hirobe,
Wakamatsu,
Ito,
Kawa,
Soma,
Mizoguchi,
- The inhibition of early N-glycan processing targets TRP-2 to degradation in B16 melanoma cells. Negroiu, G., Dwek, R.A., Petrescu, S.M. J. Biol. Chem. (2003)
- Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development. Dunn, K.J., Williams, B.O., Li, Y., Pavan, W.J. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity. Tüting, T., Steitz, J., Brück, J., Gambotto, A., Steinbrink, K., DeLeo, A.B., Robbins, P., Knop, J., Enk, A.H. The journal of gene medicine. (1999)
- Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden. Prins, R.M., Bruhn, K.W., Craft, N., Lin, J.W., Kim, C.H., Odesa, S.K., Miller, J.F., Liau, L.M. Neurosurgery (2006)
- Loss of sex discrimination and male-male aggression in mice deficient for TRP2. Stowers, L., Holy, T.E., Meister, M., Dulac, C., Koentges, G. Science (2002)
- Pheromones, vomeronasal function, and gender-specific behavior. Keverne, E.B. Cell (2002)
- Coupling and uncoupling of tumor immunity and autoimmunity. Bowne, W.B., Srinivasan, R., Wolchok, J.D., Hawkins, W.G., Blachere, N.E., Dyall, R., Lewis, J.J., Houghton, A.N. J. Exp. Med. (1999)
- Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. Rubera, I., Loffing, J., Palmer, L.G., Frindt, G., Fowler-Jaeger, N., Sauter, D., Carroll, T., McMahon, A., Hummler, E., Rossier, B.C. J. Clin. Invest. (2003)
- Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis. Kobayashi, T., Urabe, K., Winder, A., Jiménez-Cervantes, C., Imokawa, G., Brewington, T., Solano, F., García-Borrón, J.C., Hearing, V.J. EMBO J. (1994)
- A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. Tsukamoto, K., Jackson, I.J., Urabe, K., Montague, P.M., Hearing, V.J. EMBO J. (1992)
- Melatonin antagonizes alpha-melanocyte-stimulating hormone enhancement of melanogenesis in mouse melanoma cells by blocking the hormone-induced accumulation of the c locus tyrosinase. Valverde, P., Benedito, E., Solano, F., Oaknin, S., Lozano, J.A., García-Borrón, J.C. Eur. J. Biochem. (1995)
- Cytotoxic T lymphocytes responding to low dose TRP2 antigen are induced against B16 melanoma by liposome-encapsulated TRP2 peptide and CpG DNA adjuvant. Jérôme, V., Graser, A., Müller, R., Kontermann, R.E., Konur, A. J. Immunother. (2006)
- Melanocytes and pigmentation are affected in dopachrome tautomerase knockout mice. Guyonneau, L., Murisier, F., Rossier, A., Moulin, A., Beermann, F. Mol. Cell. Biol. (2004)
- Direct interaction of Sox10 with the promoter of murine Dopachrome Tautomerase (Dct) and synergistic activation of Dct expression with Mitf. Jiao, Z., Mollaaghababa, R., Pavan, W.J., Antonellis, A., Green, E.D., Hornyak, T.J. Pigment Cell Res. (2004)
- A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus. Jackson, I.J., Chambers, D.M., Tsukamoto, K., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Hearing, V. EMBO J. (1992)
- Dopachrome tautomerase is a zinc-containing enzyme. Solano, F., Martinez-Liarte, J.H., Jiménez-Cervantes, C., García-Borrón, J.C., Lozano, J.A. Biochem. Biophys. Res. Commun. (1994)
- Functional properties of cloned melanogenic proteins. Hearing, V.J., Tsukamoto, K., Urabe, K., Kameyama, K., Montague, P.M., Jackson, I.J. Pigment Cell Res. (1992)
- TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. Steel, K.P., Davidson, D.R., Jackson, I.J. Development (1992)
- Stem cell factor and/or endothelin-3 dependent immortal melanoblast and melanocyte populations derived from mouse neural crest cells. Kawa, Y., Ito, M., Ono, H., Asano, M., Takano, N., Ooka, S., Watabe, H., Hosaka, E., Baba, T., Kubota, Y., Mizoguchi, M. Pigment Cell Res. (2000)
- Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway. Wehrle-Haller, B., Weston, J.A. Development (1995)
- Molecular mechanism for catalysis by a new zinc-enzyme, dopachrome tautomerase. Solano, F., Jiménez-Cervantes, C., Martínez-Liarte, J.H., García-Borrón, J.C., Jara, J.R., Lozano, J.A. Biochem. J. (1996)
- Regulation of melanogenesis induced by 5-methoxypsoralen without ultraviolet light in murine melanoma cells. Mengeaud, V., Ortonne, J.P. Pigment Cell Res. (1994)
- Long-range activation of Sox9 in Odd Sex (Ods) mice. Qin, Y., Kong, L.K., Poirier, C., Truong, C., Overbeek, P.A., Bishop, C.E. Hum. Mol. Genet. (2004)
- Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor. Opdecamp, K., Nakayama, A., Nguyen, M.T., Hodgkinson, C.A., Pavan, W.J., Arnheiter, H. Development (1997)
- The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo. Collinson, J.M., Quinn, J.C., Hill, R.E., West, J.D. Dev. Biol. (2003)
- The slaty mutation affects eumelanin and pheomelanin synthesis in mouse melanocytes. Hirobe, T., Wakamatsu, K., Ito, S., Kawa, Y., Soma, Y., Mizoguchi, M. Eur. J. Cell Biol. (2006)
- Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation. Jiao, Z., Zhang, Z.G., Hornyak, T.J., Hozeska, A., Zhang, R.L., Wang, Y., Wang, L., Roberts, C., Strickland, F.M., Chopp, M. Dev. Biol. (2006)
- Stimulation of melanogenesis by tetradecanoylphorbol 13-acetate (TPA) in mouse melanocytes and neural crest cells. Prince, S., Wiggins, T., Hulley, P.A., Kidson, S.H. Pigment Cell Res. (2003)
- Genetic vaccination with "self" tyrosinase-related protein 2 causes melanoma eradication but not vitiligo. Bronte, V., Apolloni, E., Ronca, R., Zamboni, P., Overwijk, W.W., Surman, D.R., Restifo, N.P., Zanovello, P. Cancer Res. (2000)