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HAPLN2  -  hyaluronan and proteoglycan link protein 2

Homo sapiens

Synonyms: BRAL1, Brain link protein 1, Hyaluronan and proteoglycan link protein 2
 
 
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Disease relevance of HAPLN2

  • For example, we do need to know about pulmonary complications after head injury and cere - bral hemorrhage, manage hyperglycemia and understand its deleterious effect when left uncontrolled, and have a good knowledge of coagulopathies [1].
 

High impact information on HAPLN2

  • The human BRAL1 gene contained 7 exons and spanned approximately 6 kb [2].
  • Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1q21-23 [3].
 

Analytical, diagnostic and therapeutic context of HAPLN2

References

  1. Message from the editor. Wijdicks, E.F. Neurocritical care (2006) [Pubmed]
  2. The brain link protein-1 (BRAL1): cDNA cloning, genomic structure, and characterization as a novel link protein expressed in adult brain. Hirakawa, S., Oohashi, T., Su, W.D., Yoshioka, H., Murakami, T., Arata, J., Ninomiya, Y. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
  3. Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1q21-23. Nomoto, H., Oohashi, T., Hirakawa, S., Ueki, Y., Ohtsuki, H., Ninomiya, Y. Acta Med. Okayama (2002) [Pubmed]
 
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