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Gene Review:

ZSCAN31 - zinc finger and SCAN domain containing 31

Homo sapiens

Synonyms: ZNF20-Lp, ZNF310P, ZNF323, Zinc finger and SCAN domain-containing protein 31, Zinc finger protein 323, ...

Pi, H. et al.

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High impact information on ZNF323

A novel human SCAN/(Cys)2(His)2 zinc-finger transcription factor ZNF323 in early human embryonic development [1].
In adult tissues, ZNF323 is expressed at high levels in liver and kidney, weakly in lung, pancreas, brain, placenta, muscle, and heart [1].
ZNF323 maps to chromosome 6p22.1-22 [1].
Here, we have identified and characterized a novel zinc-finger gene named ZNF323 using degenerate primers from an early human embryo heart cDNA library [1].

Biological context of ZNF323

Taken together, these results indicate that ZNF323 is a member of the zinc-finger transcription factor family and may be involved in the development of multiple embryonic organs [1].

Analytical, diagnostic and therapeutic context of ZNF323

Northern blot analysis shows that a 3.2-kb transcript specific for ZNF323 was expressed at high levels in the lung, liver, and kidney, while weakly expressed in intestine, brain, muscle, cholecyst, heart, and pancreas [1].

References

A novel human SCAN/(Cys)2(His)2 zinc-finger transcription factor ZNF323 in early human embryonic development. Pi, H., Li, Y., Zhu, C., Zhou, L., Luo, K., Yuan, W., Yi, Z., Wang, Y., Wu, X., Liu, M. Biochem. Biophys. Res. Commun. (2002) [Pubmed]

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ZSCAN31	Bos taurus
ZSCAN12	Macaca mulatta
ZSCAN31	Pan troglodytes

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