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CRTC3  -  CREB regulated transcription coactivator 3

Homo sapiens

Synonyms: CREB-regulated transcription coactivator 3, FLJ21868, TORC-3, TORC3, Transducer of CREB protein 3, ...
 
 
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Disease relevance of CRTC3

  • By using a luciferase assay system, we show that TORC3 alone can enhance transcription from the HTLV-I LTR, as well as from a cellular cyclic AMP-response element (CRE) [1].
 

High impact information on CRTC3

 

Associations of CRTC3 with chemical compounds

References

  1. Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3. Koga, H., Ohshima, T., Shimotohno, K. J. Biol. Chem. (2004) [Pubmed]
  2. Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1{alpha} transcription and mitochondrial biogenesis in muscle cells. Wu, Z., Huang, X., Feng, Y., Handschin, C., Feng, Y., Gullicksen, P.S., Bare, O., Labow, M., Spiegelman, B., Stevenson, S.C. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
 
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