Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

SOX15 - SRY (sex determining region Y)-box 15

Homo sapiens

Synonyms: Protein SOX-12, Protein SOX-15, Protein SOX-20, SOX12, SOX20, ...

Hiraoka, Y. et al., Meyer, J. et al., Critcher, R. et al.

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High impact information on SOX15

Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3 [1].
SOX20, a new member of the SOX gene family, is located on chromosome 17p13 [2].
A data base search revealed a high similarity of the deduced amino acid sequence to the human SOX12 and the murine Sox16 HMG domains [2].
Isolation and expression of a human SRY-related cDNA hSOX20 [3].
Various adult and fetal tissues were tested for hSOX20 mRNA by Northern analysis [3].

Anatomical context of SOX15

We have isolated and sequenced an hSOX20 cDNA from a cell line of human embryonic carcinoma [3].

Analytical, diagnostic and therapeutic context of SOX15

Electrophoretic mobility shift assay indicated that recombinant hSOX20 polypeptide is capable of binding to AACAAT sequence [3].

References

Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3. Critcher, R., Stitson, R.N., Wade-Martins, R., Easty, D.J., Farr, C.J. Cytogenet. Cell Genet. (1998) [Pubmed]
SOX20, a new member of the SOX gene family, is located on chromosome 17p13. Meyer, J., Wirth, J., Held, M., Schempp, W., Scherer, G. Cytogenet. Cell Genet. (1996) [Pubmed]
Isolation and expression of a human SRY-related cDNA hSOX20. Hiraoka, Y., Ogawa, M., Sakai, Y., Taniguchi, K., Fujii, T., Umezawa, A., Hata, J., Aiso, S. Biochim. Biophys. Acta (1998) [Pubmed]

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SOX15	Bos taurus
SOX15	Canis lupus familiaris
Sox15	Mus musculus
SOX15	Pan troglodytes

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