Gene Review:
SOX4 - SRY (sex determining region Y)-box 4
Homo sapiens
Synonyms:
Transcription factor SOX-4
- Differential expression of SOX4 and SOX11 in medulloblastoma. Lee, C.J., Appleby, V.J., Orme, A.T., Chan, W.I., Scotting, P.J. J. Neurooncol. (2002)
- Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells. Liu, P., Ramachandran, S., Ali Seyed, M., Scharer, C.D., Laycock, N., Dalton, W.B., Williams, H., Karanam, S., Datta, M.W., Jaye, D.L., Moreno, C.S. Cancer Res. (2006)
- Large scale molecular analysis identifies genes with altered expression in salivary adenoid cystic carcinoma. Frierson, H.F., El-Naggar, A.K., Welsh, J.B., Sapinoso, L.M., Su, A.I., Cheng, J., Saku, T., Moskaluk, C.A., Hampton, G.M. Am. J. Pathol. (2002)
- Regulation of the expression and activity by progestins of a member of the SOX gene family of transcriptional modulators. Graham, J.D., Hunt, S.M., Tran, N., Clarke, C.L. J. Mol. Endocrinol. (1999)
- Molecular and immunological evaluation of the transcription factor SOX-4 as a lung tumor vaccine antigen. Friedman, R.S., Bangur, C.S., Zasloff, E.J., Fan, L., Wang, T., Watanabe, Y., Kalos, M. J. Immunol. (2004)
- Cytokine-specific transcriptional regulation through an IL-5Ralpha interacting protein. Geijsen, N., Uings, I.J., Pals, C., Armstrong, J., McKinnon, M., Raaijmakers, J.A., Lammers, J.W., Koenderman, L., Coffer, P.J. Science (2001)
- The establishment of neuronal properties is controlled by Sox4 and Sox11. Bergsland, M., Werme, M., Malewicz, M., Perlmann, T., Muhr, J. Genes Dev. (2006)
- The high mobility group transcription factor, SOX4, transactivates the human CD2 enhancer. Wotton, D., Lake, R.A., Farr, C.J., Owen, M.J. J. Biol. Chem. (1995)
- Characterization and mapping of the human SOX4 gene. Farr, C.J., Easty, D.J., Ragoussis, J., Collignon, J., Lovell-Badge, R., Goodfellow, P.N. Mamm. Genome (1993)
- Functional identification of the pro-apoptotic effector domain in human Sox4. Hur, E.H., Hur, W., Choi, J.Y., Kim, I.K., Kim, H.Y., Yoon, S.K., Rhim, H. Biochem. Biophys. Res. Commun. (2004)
- SOX4 expression in bladder carcinoma: clinical aspects and in vitro functional characterization. Aaboe, M., Birkenkamp-Demtroder, K., Wiuf, C., Sørensen, F.B., Thykjaer, T., Sauter, G., Jensen, K.M., Dyrskjøt, L., Ørntoft, T. Cancer Res. (2006)
- Effect of overexpression of progesterone receptor A on endogenous progestin-sensitive endpoints in breast cancer cells. McGowan, E.M., Clarke, C.L. Mol. Endocrinol. (1999)
- Ubc9 interacts with SOX4 and represses its transcriptional activity. Pan, X., Li, H., Zhang, P., Jin, B., Man, J., Tian, L., Su, G., Zhao, J., Li, W., Liu, H., Gong, W., Zhou, T., Zhang, X. Biochem. Biophys. Res. Commun. (2006)
- Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3. Critcher, R., Stitson, R.N., Wade-Martins, R., Easty, D.J., Farr, C.J. Cytogenet. Cell Genet. (1998)
- Sox-4 messenger RNA is expressed in the embryonic growth plate and regulated via the parathyroid hormone/parathyroid hormone-related protein receptor in osteoblast-like cells. Reppe, S., Rian, E., Jemtland, R., Olstad, O.K., Gautvik, V.T., Gautvik, K.M. J. Bone Miner. Res. (2000)
- Knockdown of Sox4 expression by RNAi induces apoptosis in ACC3 cells. Pramoonjago, P., Baras, A.S., Moskaluk, C.A. Oncogene (2006)