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Gene Review

HMGN5  -  high mobility group nucleosome binding...

Homo sapiens

Synonyms: High mobility group nucleosome-binding domain-containing protein 5, NBP-45, NSBP1, Nucleosome-binding protein 1
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Disease relevance of NSBP1

  • Identical questionnaires were given to a group of 51 patients with non-specific back pain (NSBP) attending an orthopaedic clinic [1].
  • CONCLUSION: This study suggests that hyperglycemia and higher NSBP levels should be responsible for an increased prevalence of LVH in hypertensive patients with Type 2 DM [2].

High impact information on NSBP1


  1. Ankylosing spondylitis and trauma: the medicolegal implications. A comparative study of patients with non-specific back pain. Jacoby, R.K., Newell, R.L., Hickling, P. Ann. Rheum. Dis. (1985) [Pubmed]
  2. Hyperglycemia and nocturnal systolic blood pressure are associatedwith left ventricular hypertrophy and diastolic dysfunction in hypertensive diabetic patients. Fel??cio, J.S., Pacheco, J.T., Ferreira, S.R., Plavnik, F., Mois??s, V.A., Kohlmann, O., Ribeiro, A.B., Zanella, M.T. Cardiovascular diabetology [electronic resource]. (2006) [Pubmed]
  3. The chromatin unfolding domain of chromosomal protein HMG-14 targets the N-terminal tail of histone H3 in nucleosomes. Trieschmann, L., Martin, B., Bustin, M. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  4. Retropseudogenes for human chromosomal protein HMG-17. Srikantha, T., Landsman, D., Bustin, M. J. Mol. Biol. (1987) [Pubmed]
  5. Characterization of a human gene encoding nucleosomal binding protein NSBP1. King, L.M., Francomano, C.A. Genomics (2001) [Pubmed]
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