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Gene Review:

CORO7 - coronin 7

Homo sapiens

Synonyms: 0610011B16Rik, 70 kDa WD repeat tumor rejection antigen homolog, CRN7, Coronin-7, Crn7, ...

Rybakin, V. et al., Rybakin, V. et al.

V. Rybakin, R.H. Rastetter, M. Stumpf, A.C. Uetrecht, J.E. Bear, A.A. Noegel, C.S. Clemen,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on CORO7

Crn7 is a novel cytosolic mammalian WD-repeat protein of unknown function that associates with Golgi membranes [1].
This study provides the first insight into the function of mammalian Crn7 protein in the Golgi complex [1].

Associations of CORO7 with chemical compounds

Downregulation of the mu1-subunit of AP-1 leads to the dispersal of Crn7 from the Golgi membranes [2].

Anatomical context of CORO7

We further establish that Crn7 co-precipitates with clathrin adaptor AP-1 but is not required for AP-1 targeting to Golgi membranes [1].

References

Crn7 Interacts with AP-1 and Is Required for the Maintenance of Golgi Morphology and Protein Export from the Golgi. Rybakin, V., Gounko, N.V., Sp??te, K., H??ning, S., Majoul, I.V., Duden, R., Noegel, A.A. J. Biol. Chem. (2006) [Pubmed]
Molecular mechanism underlying the association of Coronin-7 with Golgi membranes. Rybakin, V., Rastetter, R.H., Stumpf, M., Uetrecht, A.C., Bear, J.E., Noegel, A.A., Clemen, C.S. Cell. Mol. Life Sci. (2008) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP000930	Anopheles gambiae str. PEST
CORO7	Bos taurus
pod-1	Caenorhabditis elegans
CORO7	Canis lupus familiaris
coro7	Danio rerio
pod1	Drosophila melanogaster
CORO7	Gallus gallus
CORO7-PAM16	Homo sapiens
CORO7	Macaca mulatta
Coro7	Mus musculus
LOC100611215	Pan troglodytes
Coro7	Rattus norvegicus
coro7	Xenopus (Silurana) tropicalis

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