The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • OMIM
  • SNPedia
  • UniProt
  • Ensembl
  • HGNC

Table of contents

About

Terms

 

Gene Review: 

CLPB  -  ClpB caseinolytic peptidase B homolog (E....

Homo sapiens

Synonyms: Caseinolytic peptidase B protein homolog, FLJ13152, HSP78, SKD3, Suppressor of potassium transport defect 3
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of CLPB

  • This study used structured diagnostic interviews and DSM-III criteria to assess lifetime prevalence and pre-morbid risk of psychiatric disorder in a sample of men with long-standing chronic back pain (CLPB) attending a primary care clinic [1].
 

High impact information on CLPB

  • Canavanine induced the synthesis of the four high molecular weight HSPs, particularly HSP 89 and HSP 78, without noticeably enhancing synthesis of the low molecular weight HSPs [2].
  • Hsp78, the homolog of the bacterial chaperone ClpB in mitochondria of eukaryotic organisms, participates in both protective activities [3].
  • Northern analysis showed that the 2.3-kb SKD3 transcript is present in a wide variety of tissues, is abundant in mouse heart, skeletal muscle and kidney, and is most abundant in testis [4].

References

  1. Prevalence, onset, and risk of psychiatric disorders in men with chronic low back pain: a controlled study. Atkinson, J.H., Slater, M.A., Patterson, T.L., Grant, I., Garfin, S.R. Pain (1991) [Pubmed]
  2. Attenuated induction of heat shock gene expression in aging diploid fibroblasts. Liu, A.Y., Lin, Z., Choi, H.S., Sorhage, F., Li, B. J. Biol. Chem. (1989) [Pubmed]
  3. Structure and function of Hsp78, the mitochondrial ClpB homolog. Leidhold, C., Janowsky, B., Becker, D., Bender, T., Voos, W. J. Struct. Biol. (2006) [Pubmed]
  4. Expression of a putative ATPase suppresses the growth defect of a yeast potassium transport mutant: identification of a mammalian member of the Clp/HSP104 family. Périer, F., Radeke, C.M., Raab-Graham, K.F., Vandenberg, C.A. Gene (1995) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities