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Gene Review

SUR1  -  S-alkyl-thiohydroximate lyase SUR1

Arabidopsis thaliana

Synonyms: ABERRANT LATERAL ROOT FORMATION 1, ALF1, F23N11.7, F23N11_7, HLS3, ...
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Disease relevance of SUR1


High impact information on SUR1

  • We were able to phenocopy the Sur1- phenotype by supplying auxin to wild-type seedlings, to propagate sur1 explants on phytohormone-deficient medium, and to regenerate shoots from these explants by the addition of cytokinins alone to the culture medium [2].
  • Analysis by gas chromatography coupled to mass spectrometry indicated increased levels of both free and conjugated indole-3-acetic acid. sur1 was crossed to the mutant axr2 and the altered-auxin response mutant ctr1 [2].
  • The sur1 gene was mapped on chromosome 2 at 0.5 centimorgans from the gene encoding phytochrome B [2].
  • Furthermore, production of camalexin in the sur1 mutant devoid of glucosinolates excludes the possibility that camalexin is derived from indole glucosinolates [3].
  • This is evidenced by selective metabolite profiling of sur1, which is completely devoid of aliphatic and indole glucosinolates [1].

Associations of SUR1 with chemical compounds


  1. Arabidopsis mutants in the C-S lyase of glucosinolate biosynthesis establish a critical role for indole-3-acetaldoxime in auxin homeostasis. Mikkelsen, M.D., Naur, P., Halkier, B.A. Plant J. (2004) [Pubmed]
  2. Superroot, a recessive mutation in Arabidopsis, confers auxin overproduction. Boerjan, W., Cervera, M.T., Delarue, M., Beeckman, T., Dewitte, W., Bellini, C., Caboche, M., Van Onckelen, H., Van Montagu, M., Inzé, D. Plant Cell (1995) [Pubmed]
  3. Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis. Glawischnig, E., Hansen, B.G., Olsen, C.E., Halkier, B.A. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  4. Higher activity of an aldehyde oxidase in the auxin-overproducing superroot1 mutant of Arabidopsis thaliana. Seo, M., Akaba, S., Oritani, T., Delarue, M., Bellini, C., Caboche, M., Koshiba, T. Plant Physiol. (1998) [Pubmed]
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