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Chemical Compound Review

Djenkolate     (2S)-2-amino-3-[[(2S)-2- amino-2-carboxy...

Synonyms: L-Djenkolate, Djenkolic acid, Jengkolic acid, AG-K-77412, AC1Q5QNS, ...
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Disease relevance of Djenkolic acid


High impact information on Djenkolic acid

  • 7. The energy of activation with L-djenkolate as the substrate is 53.1 kJ/mol [4].
  • With either L-cystathionine and L-djenkolate as substrate, maximal activity was obtained between pH 8.3 and pH 9 [5].
  • The results suggest that CS2 production is common in the Mimosoideae and uncommon in the Caesalpinioideae and Papilionoideae and that plants in the Mimosoideae that do produce CS2 must possess both a djenkolic acid and a cysteine lyase for this production to occur [6].
  • Of nine mimosoid taxa that produced CS2, all possessed a djenkolic acid and a cysteine lyase [6].
  • When sulfate transport was enhanced by addition of djenkolic acid, Candida sp. became hypersensitive [7].

Chemical compound and disease context of Djenkolic acid

  • S-Alkylcysteine alpha, beta-lyase [EC] of Pseudomonas putida catalyzes alpha,beta-elimination of L-djenkolate [3,3'-methylenedithiobis(2-aminopropionic acid)] to produce pyruvate, ammonia, and S-(mercaptomethyl)cysteine initially [2].

Associations of Djenkolic acid with other chemical compounds

  • Of three mimosoid taxa that did not produce CS2, two lacked a cysteine lyase and one lacked both a lyase and a djenkolic acid [6].


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