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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

UBC19  -  ubiquitin-conjugating enzyme E2 19

Arabidopsis thaliana

Synonyms: ubiquitin-conjugating enzyme19
 
 
 
 
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High impact information on UBC19

  • Arabidopsis encodes two genes belonging to the E2-C gene family (called UBC19 and UBC20) [1].
  • Thus, the UBC19/20 E2s may have a key function during cell cycle, but may also be involved in ubiquitylation reactions occurring during differentiation and/or in differentiated cells [1].
  • Finally, we showed that a translational fusion protein between UBC19 and green fluorescent protein localized both in the cytosol and the nucleus in stable transformed tobacco (Nicotiana tabacum cv Bright Yellow 2) cells [1].
  • We found that UBC19 is able to complement fission yeast (Schizosaccharomyces pombe) UbcP4-140 mutant, indicating that the plant protein can functionally replace its yeast ortholog for protein degradation during mitosis [1].

References

  1. Molecular characterization of plant ubiquitin-conjugating enzymes belonging to the UbcP4/E2-C/UBCx/UbcH10 gene family. Criqui, M.C., de Almeida Engler, J., Camasses, A., Capron, A., Parmentier, Y., Inzé, D., Genschik, P. Plant Physiol. (2002) [Pubmed]
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