Gene Review:
UBE2C - ubiquitin-conjugating enzyme E2C
Homo sapiens
Synonyms:
UBCH10, UbcH10, Ubiquitin carrier protein C, Ubiquitin-conjugating enzyme E2 C, Ubiquitin-protein ligase C, ...
- Detection of aberrations of ubiquitin-conjugating enzyme E2C gene (UBE2C) in advanced colon cancer with liver metastases by DNA microarray and two-color FISH. Takahashi, Y., Ishii, Y., Nishida, Y., Ikarashi, M., Nagata, T., Nakamura, T., Yamamori, S., Asai, S. Cancer Genet. Cytogenet. (2006)
- Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma. Lin, J., Raoof, D.A., Wang, Z., Lin, M.Y., Thomas, D.G., Greenson, J.K., Giordano, T.J., Orringer, M.B., Chang, A.C., Beer, D.G., Lin, L. Neoplasia (2006)
- Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin. Wagner, K.W., Sapinoso, L.M., El-Rifai, W., Frierson, H.F., Butz, N., Mestan, J., Hofmann, F., Deveraux, Q.L., Hampton, G.M. Oncogene (2004)
- Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression. Gabellini, D., Colaluca, I.N., Vodermaier, H.C., Biamonti, G., Giacca, M., Falaschi, A., Riva, S., Peverali, F.A. EMBO J. (2003)
- Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase. Townsley, F.M., Aristarkhov, A., Beck, S., Hershko, A., Ruderman, J.V. Proc. Natl. Acad. Sci. U.S.A. (1997)
- UbcH10 is the cancer-related E2 ubiquitin-conjugating enzyme. Okamoto, Y., Ozaki, T., Miyazaki, K., Aoyama, M., Miyazaki, M., Nakagawara, A. Cancer Res. (2003)
- Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10. Lin, Y., Hwang, W.C., Basavappa, R. J. Biol. Chem. (2002)
- UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas. Pallante, P., Berlingieri, M.T., Troncone, G., Kruhoffer, M., Orntoft, T.F., Viglietto, G., Caleo, A., Migliaccio, I., Decaussin-Petrucci, M., Santoro, M., Palombini, L., Fusco, A. Br. J. Cancer (2005)
- NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase. Fortier, J.M., Kornbluth, J. J. Immunol. (2006)