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Gene Review

UBC11  -  putative E2 ubiquitin-protein ligase UBC11

Saccharomyces cerevisiae S288c

Synonyms: O6268, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2-18 kDa, Ubiquitin-protein ligase, YOR339C
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Disease relevance of UBC11

  • Gankyrin is found in other complexes that contain Rb (retinoblastoma protein) and the ubiquitin protein ligase Mdm2 (murine double minute 2) [1].

High impact information on UBC11


  1. Gankyrin, the 26 S proteasome, the cell cycle and cancer. Mayer, R.J., Fujita, J. Biochem. Soc. Trans. (2006) [Pubmed]
  2. mGrb10 interacts with Nedd4. Morrione, A., Plant, P., Valentinis, B., Staub, O., Kumar, S., Rotin, D., Baserga, R. J. Biol. Chem. (1999) [Pubmed]
  3. Functional analysis of the Saccharomyces cerevisiae UBC11 gene. Townsley, F.M., Ruderman, J.V. Yeast (1998) [Pubmed]
  4. Purification and assay of the budding yeast anaphase-promoting complex. Passmore, L.A., Barford, D., Harper, J.W. Meth. Enzymol. (2005) [Pubmed]
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